Blood Biomarkers for Evaluation of Perinatal Encephalopathy
نویسندگان
چکیده
منابع مشابه
Blood Biomarkers for Evaluation of Perinatal Encephalopathy
Recent research in identification of brain injury after trauma shows many possible blood biomarkers that may help identify the fetus and neonate with encephalopathy. Traumatic brain injury shares many common features with perinatal hypoxic-ischemic encephalopathy. Trauma has a hypoxic component, and one of the 1st physiologic consequences of moderate-severe traumatic brain injury is apnea. Trau...
متن کاملHypothermia for perinatal asphyxial encephalopathy.
BACKGROUND Perinatal asphyxial encephalopathy occurs in 1 per 1000 live births and is associated with high mortality and morbidity. Therapeutic hypothermia increases intact survival and improves neurodevelopmental outcome in survivors. AIMS To evaluate (i) the opinion and practice of therapeutic hypothermia as a therapy for moderate to severe perinatal asphyxial encephalopathy amongst Swiss n...
متن کاملPerinatal Hypoxic-Ischemic Encephalopathy
Perinatal hypoxic-ischemic encephalopathy (HIE) is an important cause of brain injury in the newborn and can result in long-term devastating consequences. Perinatal hypoxia is a vital cause of long-term neurologic complications varying from mild behavioural deficits to severe seizure, mental retardation, and/or cerebral palsy in the newborn. In the mammalian developing brain, ongoing research i...
متن کاملHypoxic-Ischemic Encephalopathy Biomarkers
Background Clinical RS for HIE are intended to determine trial entry and to compare groups within or between trials. Categorical current schemes do not reflect the broad clinical continuum spectrum of HIE and they were not design for this task. Objective To prospectively validate a new structured multi-item RS for HIE. Methods A standardised structured ordinal RS for HIE with 7 clinical items (...
متن کاملModerate hypothermia to treat perinatal asphyxial encephalopathy.
BACKGROUND Whether hypothermic therapy improves neurodevelopmental outcomes in newborn infants with asphyxial encephalopathy is uncertain. METHODS We performed a randomized trial of infants who were less than 6 hours of age and had a gestational age of at least 36 weeks and perinatal asphyxial encephalopathy. We compared intensive care plus cooling of the body to 33.5 degrees C for 72 hours a...
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ژورنال
عنوان ژورنال: Frontiers in Pharmacology
سال: 2016
ISSN: 1663-9812
DOI: 10.3389/fphar.2016.00196